Human WASH complex subunit strumpellin,KIAA0196 ELISA KIT

SKU: E6407Hu

Size:96 Tests-1 Kit

Background:Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). May be involved in axonal outgrowth. Involved in cellular localization of ADRB2 (PubMed:23085491). Involved in cellular trafficking of BLOC-1 complex cargos such as ATP7A and VAMP7 (PubMed:23676666). {ECO:0000269|PubMed:19922875, ECO:0000269|PubMed:20833645, ECO:0000269|PubMed:23085491, ECO:0000269|PubMed:23676666}.

Research_area:

Applications:ELISA

Target_protein:WASHC5

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.75ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:WASH complex subunit strumpellin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q12768

MASS(Da):134286

GeneID:9897

Synonyms:WASHC5 KIAA0196

Gene names:WASHC5

Standard solution:2400ng/L