Human Udp-Glucose 4-Epimerase, GALE ELISA Kit

SKU: E4621Hu

Size:96 Tests-1 Kit

Background:Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.

Research_area:Others

Applications:ELISA

Target_protein:GALE

Reactivity:Human

Assay type:Sandwich

Sensitivity:8.07ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Udp-Glucose 4-Epimerase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q14376

MASS(Da):38,282

GeneID:2582

Synonyms:Galactowaldenase;GALE;UDP-galactose 4-epimerase;UDP-GalNAc 4-epimerase;UDP-GlcNAc 4-epimerase;UDP-glucose 4-epimerase;UDP-N-acetylgalactosamine 4-epimerase;UDP-N-acetylglucosamine 4-epimerase

Gene names:GALE

Standard solution:3200ng/L