Human Thyroxine 5-Deiodinase, DIO3 ELISA Kit

SKU: E2462Hu

Size:96 Tests-1 Kit

Background:Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.

Research_area:Others

Applications:ELISA

Target_protein:DIO3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.098ng/ml

Detection range:0.2-70ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Thyroxine 5-Deiodinase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P55073

MASS(Da):33,947

GeneID:1735

Synonyms:5DIII;DIO 3;DIO3;DIOIII;Thyroxine 5-deiodinase;Type 3 DI;Type III iodothyronine deiodinase

Gene names:DIO3

Standard solution:80ng/ml