Human Thioredoxin, TRX ELISA Kit

SKU: E1452Hu

Size:96 Tests-1 Kit

Background:Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (PubMed: 2176490, PubMed: 17182577, PubMed: 19032234). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity (PubMed: 16408020, PubMed: 17606900). Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity (PubMed: 9108029, PubMed: 11118054). ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).

Research_area:Metabolism

Applications:ELISA

Target_protein:TXN

Reactivity:Human

Assay type:Sandwich

Sensitivity:2.49U/L

Detection range:5-1500U/L

Sample type:Serum, plasma or other biological fluids

Full product name:Thioredoxin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P10599

MASS(Da):11,737

GeneID:7295

Synonyms:ADF;allergen Hom s Trx;ATL-derived factor;SASP;Surface-associated sulphydryl protein;Thioredoxin;Trx;TXN

Gene names:TXN

Standard solution:1600U/L