Human TFPI / Tissue Factor Pathway Inhibitor ELISA Kit PicoKine®

SKU: EK0840

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: TFPI

Specificity: Natural and recombinant human TFPI

Background: TFPI (Tissue factor pathway inhibitor),also known as EPI, LACI or TFPI1, is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) and Thrombin (Factor IIa). The gene for TFPI is located on chromosome 2q31-q32.1, and has nine exons which span 70 kb. TFPI consists of a highly negatively-charged amino-terminus, three tandemly-linked Kunitz domains, and a highly positively-charged carboxy-terminus.TFPI contributes significantly to the inhibition of Xa in vivo, despite being present at concentrations of only 2.5 nM.

Immunogen: Expression system for standard: NS0; Immunogen sequence: D29-K282

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Reference:

Uniprot ID: P10646

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 7035

Protein Name: Tissue factor pathway inhibitor

Gene Full Name: tissue factor pathway inhibitor

Synonyms: EPI; Extrinsic pathway inhibitor; LACI; TFI; TFPI; TFPI1