Human Steroid Hormone Receptor Err1, ESRRA ELISA Kit

SKU: E6223Hu

Size:96 Tests-1 Kit

Background:Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:ESRRA

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.84ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Steroid hormone receptor ERR1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P11474

MASS(Da):45,510

GeneID:2101

Synonyms:ERR1;ERRa;ERRalpha;ERR-alpha;ESRL1;ESRRA;Estrogen receptor-like 1;Estrogen-related receptor alpha;NR3B1;Nuclear receptor subfamily 3 group B member 1;Steroid hormone receptor ERR1

Gene names:ESRRA

Standard solution:4800ng/L