Human Single Ig IL-1-related receptor,SIGIRR;TIR8 ELISA KIT

SKU: E4432Hu

Size:96 Tests-1 Kit

Background:Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. {ECO:0000269|PubMed:12925853, ECO:0000269|PubMed:14715412, ECO:0000269|PubMed:15866876, ECO:0000269|PubMed:25963006}.

Research_area:

Applications:ELISA

Target_protein:SIGIRR

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.28ng/ml

Detection range:0.5-200ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Single Ig IL-1-related receptor

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q6IA17

MASS(Da):45679

GeneID:59307

Synonyms:SIGIRR UNQ301/PRO342

Gene names:SIGIRR

Standard solution:240ng/ml