Human SHBG / Sex Hormone Binding Globulin ELISA Kit PicoKine®

SKU: EK1236

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: SHBG

Specificity: Natural and recombinant human SHBG

Background: Sex hormone-binding globulin (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to the two sex hormones: androgen and estrogen. The gene for SHBG is located on chromosome 17 on the short arm between the bands 17p12→p13. And this gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L30-H402

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Reference:

Uniprot ID: P04278

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 6462

Protein Name: Sex hormone-binding globulin

Gene Full Name: Sex hormone-binding globulin

Synonyms: Sex hormone-binding globulin;SHBG;Sex steroid-binding protein;SBP;Testis-specific androgen-binding protein;ABP;Testosterone-estradiol-binding globulin;TeBG;Testosterone-estrogen-binding globulin;SHBG;