Human Semaphorin 5A, SEMA5A ELISA Kit

SKU: E1945Hu

Size:96 Tests-1 Kit

Background:Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.

Research_area:Others

Applications:ELISA

Target_protein:SEMA5A

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.02ng/ml

Detection range:0.05-10ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Semaphorin 5A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13591

MASS(Da):120,615

GeneID:9037

Synonyms:Sema F;SEMA5A;Semaphorin-5A;Semaphorin-F

Gene names:SEMA5A

Standard solution:12.8ng/ml