Human SDF-1/CXCL12 ELISA Kit PicoKine®

SKU: EK0499

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CXCL12

Specificity: Natural and recombinant human CXCL12

Background: The stromal cell-derived factor 1 (SDF-1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein that in humans is encoded by the CXCL12 gene on chromosome 10. This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: V24-M93

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Uniprot ID: P48061

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 6387

Protein Name: Stromal cell-derived factor 1

Gene Full Name: C-X-C motif chemokine ligand 12

Synonyms: C X C motif chemokine 12; CXCL12; CXCL12/SDF-1; hIRH; hSDF 1; IRH; PBSF; SCYB12; SDF 1; SDF 1a; SDF 1b; SDF1; SDF-1; SDF1A; SDF1B; Stromal cell derived factor 1; TLSF a; TLSF b; TPAR1