Human S100A8/Calgranulin A ELISA Kit PicoKine®

SKU: EK1558

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: S100A8

Specificity: Natural and recombinant human S100A8

Background: S100 calcium-binding protein A8 (S100A8), also known as calgranulin A, is a protein that in humans is encoded by the S100A8 gene. It is mapped to chromosome 1q21.3 based on an alignment of the S100A8 sequence with the genomic sequence. The proteins S100A8 and S100A9 form a heterodimer called calprotectin which is a major calcium- and zinc-binding protein in the cytosol of neutrophils, monocytes, and keratinocytes. This gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. And S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: L2-E93

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Uniprot ID: P05109

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 6279

Protein Name: Protein S100-A8

Gene Full Name: S100 calcium binding protein A8

Synonyms: 60B8AG; CAGA; Calgranulin A; Calprotectin L1L subunit; CFAG; CGLA; CP 10; Cystic fibrosis antigen; L1Ag; MA387; MIF; MRP 8; MRP8; NIF; P8; Protein S100 A8; S100A8; Urinary stone protein band A