Human Rna Polymerase Ii Subunit A C-terminal Domain Phosphatase, CTDP1 ELISA Kit

SKU: E6507Hu

Size:96 Tests-1 Kit

Background:Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation.

Research_area:Signal Transduction; Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:CTDP1

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.32ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:RNA polymerase II subunit A C-terminal domain phosphatase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9Y5B0

MASS(Da):104,399

GeneID:9150

Synonyms:CCFDN;CTDP1;FCP1;RNA polymerase II subunit A C-terminal domain phosphatase;TFIIF-associating CTD phosphatase

Gene names:CTDP1

Standard solution:4800ng/L