Human RIO Kinase 3,RIOK3 ELISA KIT

SKU: E2932Hu

Size:96 Tests-1 Kit

Background:Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitment of TBK1 to IRF3 (PubMed:24807708). Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling (PubMed:25865883). Can inhibit CASP10 isoform 7-mediated activation of the NF-kappaB signaling pathway (PubMed:19557502). May play a role in the biogenesis of the 40S ribosomal subunit. Involved in the processing of 21S pre-rRNA to the mature 18S rRNA (PubMed:22418843). {ECO:0000269|PubMed:19557502, ECO:0000269|PubMed:22418843, ECO:0000269|PubMed:24807708, ECO:0000269|PubMed:25865883}.

Research_area:

Applications:ELISA

Target_protein:RIOK3

Reactivity:Human

Assay type:Sandwich

Sensitivity:10.73pg/ml

Detection range:18.75-1200pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:RIO Kinase 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O14730

MASS(Da):59093

GeneID:8780

Synonyms:RIOK3 SUDD

Gene names:RIOK3

Standard solution:2400pg/ml