Human ring finger protein 113A,RNF113A ELISA KIT

SKU: E7315Hu

Size:96 Tests-1 Kit

Background:Required for pre-mRNA splicing as component of the spliceosome (PubMed:29361316, PubMed:29360106). E3 ubiquitin-protein ligase that catalyzes the transfer of ubiquitin onto target proteins (PubMed:28978524, PubMed:29144457). Catalyzes polyubiquitination of SNRNP200/BRR2 with non-canonical 'Lys-63'-linked polyubiquitin chains (PubMed:29144457). Plays a role in DNA repair via its role in the synthesis of 'Lys-63'-linked polyubiquitin chains that recruit ALKBH3 and the ASCC complex to sites of DNA damage by alkylating agents (PubMed:29144457). Ubiquitinates CXCR4, leading to its degradation, and thereby contributes to the termination of CXCR4 signaling (PubMed:28978524). {ECO:0000269|PubMed:28978524, ECO:0000269|PubMed:29144457, ECO:0000269|PubMed:29360106, ECO:0000269|PubMed:29361316}.

Research_area:

Applications:ELISA

Target_protein:RNF113A

Reactivity:Human

Assay type:Sandwich

Sensitivity:3.55ng/L

Detection range:7-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:ring finger protein 113A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O15541

MASS(Da):38787

GeneID:7737

Synonyms:RNF113A RNF113 ZNF183

Gene names:RNF113A

Standard solution:1600ng/L