Human Receptor tyrosine-protein kinase erbB-3,ERBB3 ELISA KIT

SKU: E7503Hu

Size:96 Tests-1 Kit

Background:Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134). Involved in the regulation of myeloid cell differentiation (PubMed:27416908). {ECO:0000269|PubMed:15358134, ECO:0000269|PubMed:20682778, ECO:0000269|PubMed:27416908}.

Research_area:

Applications:ELISA

Target_protein:ERBB3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.014ng/ml

Detection range:0.05-15ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Receptor tyrosine-protein kinase erbB-3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P21860

MASS(Da):148098

GeneID:2065

Synonyms:ERBB3 HER3

Gene names:ERBB3

Standard solution:16ng/ml