Human RBP4/Retinol Binding Protein 4 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ0831

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: RBP4

Specificity: Natural and recombinant human RBP4

Background: Retinol binding protein 4, plasma, also known as RBP4, belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It is protein that in humans is encoded by the RBP4 gene. RBP4 gene resides just centromeric of the cluster of CYP2C genes on 10q24. The mouse Rbp4 locus is closely linked and just proximal to the locus for phenobarbital-inducible cytochrome P450-2c (Cyp-2c) at the distal end of chromosome 19. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. The standard used in this kit is recombinant protein, with E19-L201 aa sequence, the molecular weight is 22kda.

Immunogen: Expression system for standard: NS0; Immunogen sequence: E19-L201

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Reference:

Uniprot ID: P02753

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 5950

Protein Name: Retinol-binding protein 4

Gene Full Name: retinol binding protein 4

Synonyms: Plasma retinol binding protein; PRBP; RBP; RBP4; Retinol binding protein 4