Human Protein Wnt-7A,WNT7A ELISA KIT

SKU: E2353Hu

Size:96 Tests-1 Kit

Background:Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development (PubMed:16826533). Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (PubMed:30026314). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes (By similarity). Required for normal neural stem cell proliferation in the hippocampus dentate gyrus (By similarity). Required for normal progress through the cell cycle in neural progenitor cells, for self-renewal of neural stem cells, and for normal neuronal differentiation and maturation (By similarity). Promotes formation of synapses via its interaction with FZD5 (By similarity). {ECO:0000250|UniProtKB:P24383, ECO:0000269|PubMed:16826533, ECO:0000269|PubMed:30026314}.

Research_area:

Applications:ELISA

Target_protein:WNT7A

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.028ng/ml

Detection range:0.05-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Protein Wnt-7A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O00755

MASS(Da):39005

GeneID:7476

Synonyms:WNT7A

Gene names:WNT7A

Standard solution:32ng/ml