Human Protein Hook Homolog 3, HOOK3 ELISA Kit

SKU: E5981Hu

Size:96 Tests-1 Kit

Background:Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494). FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (PubMed:32073997). (Microbial infection) May serve as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking.

Research_area:Others

Applications:ELISA

Target_protein:HOOK3

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.41ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Protein Hook homolog 3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q86VS8

MASS(Da):83,126

GeneID:84376

Synonyms:hHK3;h-hook3;HK3;HOOK3;Protein Hook homolog 3

Gene names:HOOK3

Standard solution:3200ng/L