Human Plexin A3, PLXNA3 ELISA Kit

SKU: E2633Hu

Size:96 Tests-1 Kit

Background:Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

Research_area:Neuroscience

Applications:ELISA

Target_protein:PLXNA3

Reactivity:Human

Assay type:Sandwich

Sensitivity:3.32ng/L

Detection range:7-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Plexin A3

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P51805

MASS(Da):207,703

GeneID:55558

Synonyms:6.3;HSSEXGENE;Plexin-4;Plexin-A3;PLXN3;PLXN4;PLXNA3;Semaphorin receptor SEX;XAP-6;

Gene names:PLXNA3

Standard solution:1600ng/L