Human PKLR ELISA Kit PicoKine®

SKU: EK2257

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: PKLR

Specificity: Natural and recombinant human PKLR

Background: Pyruvate kinase PKLR is an enzyme that in humans is encoded by the PKLR gene. The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: L47-S574

Clonality:

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Reconstitution:

Reference:

Uniprot ID: P30613

Host:

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Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

Clone Number:

Observed Molecular Weight:

Calculated Molecular Weight:

Gene ID: 5313

Protein Name: Pyruvate kinase PKLR

Gene Full Name: pyruvate kinase L/R

Synonyms: PK1; PKL; PKLR; PKR; PKRL; Pyruvate kinase 1; Pyruvate kinase isozymes R/L; pyruvate kinase; liver and RBC; R type/L type pyruvate kinase; Red cell/liver pyruvate kinase; RPK