Human Phospholipase C Zeta 1,PLCZ1 ELISA KIT

SKU: E7402Hu

Size:96 Tests-1 Kit

Background:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function. {ECO:0000250|UniProtKB:Q8K4D7, ECO:0000269|PubMed:12416999, ECO:0000269|PubMed:14697805, ECO:0000269|PubMed:15579586, ECO:0000269|PubMed:26721930, ECO:0000305}.

Research_area:

Applications:ELISA

Target_protein:PLCZ1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.03ng/ml

Detection range:0.05-30ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Phospholipase C Zeta 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q86YW0

MASS(Da):70411

GeneID:89869

Synonyms:PLCZ1

Gene names:PLCZ1

Standard solution:32ng/ml