Human Peroxisome Proliferator-activated Receptor Gamma Coactivator 1 Beta, PGC1B ELISA Kit

SKU: E3510Hu

Size:96 Tests-1 Kit

Background:Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.

Research_area:Others

Applications:ELISA

Target_protein:PPARGC1B

Reactivity:Human

Assay type:Sandwich

Sensitivity:15.24ng/L

Detection range:30-9000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1 Beta

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q86YN6

MASS(Da):113,222

GeneID:133522

Synonyms:Peroxisome proliferator-activated receptor gamma coactivator 1-beta;PGC-1-beta;PGC-1-related estrogen receptor alpha coactivator;PPAR-gamma coactivator 1-beta;PPARGC1B;PPARGC-1-beta

Gene names:PPARGC1B

Standard solution:9600ng/L