Human Peptidyl-prolyl cis-trans isomerase FKBP6,FKBP6 ELISA KIT

SKU: E5846Hu

Size:96 Tests-1 Kit

Background:Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:FKBP6

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.35ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Peptidyl-prolyl cis-trans isomerase FKBP6

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O75344

MASS(Da):37214

GeneID:8468

Synonyms:FKBP6 FKBP36

Gene names:FKBP6

Standard solution:3200ng/L