Human Neural-Cadherin, N-CAD ELISA Kit

SKU: E0305Hu

Size:96 Tests-1 Kit

Background:Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.

Research_area:Cancer

Applications:ELISA

Target_protein:CDH2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.73ng/ml

Detection range:1-400ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Neural-Cadherin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P19022

MASS(Da):99,809

GeneID:1000

Synonyms:Cadherin-2;CD antigen CD325;CDH 2;CDH2;CDw325;N-cadherin;Neural cadherin

Gene names:CDH2

Standard solution:480ng/ml