Human Myocyte-specific Enhancer Factor 2A, MEF2A ELISA Kit

SKU: E4439Hu

Size:96 Tests-1 Kit

Background:Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

Research_area:Neuroscience

Applications:ELISA

Target_protein:MEF2A

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.93ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Myocyte-Specific Enhancer Factor 2A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q02078

MASS(Da):54,811

GeneID:4205

Synonyms:MEF2A;Myocyte-specific enhancer factor 2A;Serum response factor-like protein 1

Gene names:MEF2A

Standard solution:2400ng/L