Human Meprin A Subunit Beta, MEP1B ELISA Kit

SKU: E5663Hu

Size:96 Tests-1 Kit

Background:Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components.

Research_area:Cell Biology

Applications:ELISA

Target_protein:MEP1B

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.027ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Meprin A subunit beta

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q16820

MASS(Da):79,571

GeneID:4225

Synonyms:Endopeptidase-2;MEP1B;Meprin A subunit beta;Meprin B;N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta;PABA Peptide hydrolase;PPH beta

Gene names:MEP1B

Standard solution:24ng/mL