Human MEGF9 ELISA Kit PicoKine®

SKU: EK2278

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: MEGF9

Specificity: Natural and recombinant human MEGF9

Background: MEGF9 (Multiple EGF?like domains protein 9; also EGF?like protein 5) is a 63 kDa (predicted) novel transmembrane glycoprotein that shares some homology to beta?chains of laminin. It is expressed by hepatocytes, cerebellar Purkinje cells, Schwann cells, keratinocytes and intestinal epithelium. MEGF9 is suggested to participate in cell motility, and its absence correlates with tumor cell migration. Mature human MEGF9 is 572 amino acids (aa) in length. It is a single span type I transmembrane protein that contains a 484 aa extracellular region (aa 31?514) plus a 68 aa C?terminal cytoplasmic domain. The extracellular region possesses a lengthy Pro?rich region (aa 55?200), followed by five EGF?like domains (aa 204?451). MEGF9 may run at approximately 160 kDa in SDS?PAGE, suggesting either heavy glycosylation or dimerization. Over aa 36?514, human MEGF9 shares 76% aa sequence identity with mouse MEGF9.

Immunogen: Expression system for standard: NS0; Immunogen sequence: A36-N514

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Reference:

Uniprot ID: Q9H1U4

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 1955

Protein Name: Multiple epidermal growth factor-like domains protein 9

Gene Full Name: multiple EGF like domains 9

Synonyms: EGFL5; MEGF9; MEGF9 Ens; multiple EGF like domains 9