Human Matrix Metalloproteinase-17, MMP17 ELISA Kit

SKU: E5645Hu

Size:96 Tests-1 Kit

Background:Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.

Research_area:Others

Applications:ELISA

Target_protein:MMP17

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.029ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Matrix Metalloproteinase-17

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9ULZ9

MASS(Da):66,653

GeneID:4326

Synonyms:Matrix Metalloproteinase-17;Membrane-type Matrix Metalloproteinase 4;Membrane-type-4 Matrix Metalloproteinase;MMP 17;MMP17;MMP-17;MT4MMP;MT4-MMP;MT-MMP 4;MTMMP4

Gene names:MMP17

Standard solution:24ng/mL