Human Mannan-binding lectin,MBP ELISA KIT

SKU: E7458Hu

Size:96 Tests-1 Kit

Background:The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation. {ECO:0000269|PubMed:8544862}.

Research_area:

Applications:ELISA

Target_protein:MBP

Reactivity:Human

Assay type:Sandwich

Sensitivity:8.79ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Mannose Binding Protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P02686

MASS(Da):33117

GeneID:4155

Synonyms:MBP

Gene names:MBP

Standard solution:3200ng/L