Human LYVE-1 ELISA Kit PicoKine®

SKU: EK0967

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: LYVE1

Specificity: Natural and recombinant human LYVE-1

Background: Extracellular link domain containing 1, also known as LYVE-1 or XLKD1 is a human gene. The International Radiation Hybrid Mapping Consortium mapped the LYVE1 gene to chromosome 11p15.4. This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. This gene may play a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Immunogen: Expression system for standard: NS0; Immunogen sequence: S24-T238

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Reference:

Uniprot ID: Q9Y5Y7

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 10894

Protein Name: Lymphatic vessel endothelial hyaluronic acid receptor 1

Gene Full Name: lymphatic vessel endothelial hyaluronan receptor 1

Synonyms: CRSBP 1; CRSBP1; HAR; Hyaluronic acid receptor; LYVE 1; LYVE1; XLKD1