Human Lipoprotein Lipase, LPL ELISA Kit

SKU: E1517Hu

Size:96 Tests-1 Kit

Background:Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage (PubMed: 8675619, PubMed: 11342582, PubMed: 27578112). Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity (PubMed: 7592706, PubMed: 12032167). Mediates margination of triglyceride-rich lipoprotein particles in capillaries (PubMed: 24726386). Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (PubMed: 11342582, PubMed: 27811232).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:LPL

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.49pg/ml

Detection range:10-4000pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Lipoprotein Lipase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P06858

MASS(Da):53,162

GeneID:4023

Synonyms:Lipoprotein lipase;LPL;Phospholipase A1

Gene names:LPL

Standard solution:4800pg/ml