Human Krueppel-like Factor 4, KLF4 ELISA Kit

SKU: E5546Hu

Size:96 Tests-1 Kit

Background:Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:KLF4

Reactivity:Human

Assay type:Sandwich

Sensitivity:5.31ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Krueppel-Like Factor 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O43474

MASS(Da):54,671

GeneID:9314

Synonyms:Epithelial zinc finger protein EZF;Gut-enriched krueppel-like factor;KLF 4;KLF4;Krueppel-like factor 4

Gene names:KLF4

Standard solution:2560ng/L