Human Interleukin 21, IL-21 ELISA Kit

SKU: E0057Hu

Size:96 Tests-1 Kit

Background:Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (PubMed: 11081504, PubMed: 15178704). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity).

Research_area:Immunology; Cancer

Applications:ELISA

Target_protein:IL21

Reactivity:Human

Assay type:Sandwich

Sensitivity:2.46ng/L

Detection range:5-1500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Interleukin 21

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9HBE4

MASS(Da):18,653

GeneID:59067

Synonyms:IL 21;IL21;IL-21;Interleukin-21;Za11

Gene names:IL21

Standard solution:1600ng/L