Human Interleukin 16, IL-16 ELISA Kit

SKU: E0096Hu

Size:96 Tests-1 Kit

Background:Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. [Isoform 1]: may act as a scaffolding protein that anchors ion Channels in the membrane. Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.

Research_area:Immunology

Applications:ELISA

Target_protein:IL16

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.47ng/L

Detection range:3-900ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Interleukin 16

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q14005

MASS(Da):141752

GeneID:3603

Synonyms:IL 16;IL16;IL-16;LCF;Lymphocyte chemoattractant factor;Pro-interleukin-16 Interleukin-16

Gene names:IL16

Standard solution:960ng/L