Human Interferon Alpha/Beta Receptor 2, IFNAR2 ELISA Kit

SKU: E5493Hu

Size:96 Tests-1 Kit

Background:Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation (PubMed: 26424569, PubMed: 32972995). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1 (PubMed: 8181059, PubMed: 7665574, PubMed: 7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity (PubMed: 7759950).

Research_area:Immunology

Applications:ELISA

Target_protein:IFNAR2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.026ng/ml

Detection range:0.05-10ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Interferon Alpha/Beta Receptor 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P48551

MASS(Da):57,759

GeneID:3455

Synonyms:IFN-alpha binding protein;IFN-alpha/beta receptor 2;IFNAR 2;IFNAR2;IFN-R-2;Interferon alpha binding protein;Interferon alpha/beta receptor 2;Type I interferon receptor 2

Gene names:IFNAR2

Standard solution:24ng/ml