Human Intelectin-1, ITLN1 ELISA Kit

SKU: E0155Hu

Size:96 Tests-1 Kit

Background:Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed: 11313366, PubMed: 26148048). Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) (PubMed: 26148048). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris (PubMed: 26148048). Does not bind human glycans (PubMed: 26148048). Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes (PubMed: 16531507). Increases AKT phosphorylation in the absence and presence of insulin (PubMed: 16531507). May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (PubMed: 11747454, PubMed: 23921499).

Research_area:Cardiovascular

Applications:ELISA

Target_protein:ITLN1

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.03ng/L

Detection range:2-600ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Intelectin-1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8WWA0

MASS(Da):34,962

GeneID:55600

Synonyms:Endothelial lectin HL-1;Galactofuranose-binding lectin;Intelectin-1;Intestinal lactoferrin receptor;ITLN 1;ITLN1;ITLN-1;Omentin

Gene names:ITLN1

Standard solution:640ng/L