Human IL-37/IL-1F7 ELISA Kit PicoKine®

SKU: EK1363

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IL37

Specificity: Natural and recombinant human IL-37

Background: Interleukin 37 (IL-37) also named IL1F7, is a protein that in humans is encoded by the IL1F7 gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. And it is mapped to 2q13. In vitro expression analysis showed that IL-37 was a secretory protein. And IL-37 could play an important role in the link between innate and adaptive immunity and may be useful for tumor immunotherapy. Meanwhile, IL-37 inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells of patients with systemic lupus erythematosus. In addition, IL-37 can emerged as a dual-function cytokine with intra- and extracellular properties for suppressing innate inflammation. Furthermore, IL-37 is a new anti-inflammatory cytokine that plays an important role in protecting against tissue injury during infections via limiting immune and inflammatory reactions.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: V46-D218

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Uniprot ID: Q9NZH6

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 27178

Protein Name: Interleukin-37

Gene Full Name: interleukin 37

Synonyms: FIL1; FIL1 zeta; FIL1(ZETA); FIL1Z; IL 1 zeta; IL 1F7; IL 1H4; IL 1RP1; IL 1X; IL1F7; IL-1F7; IL1H4; IL1RP1; IL-37; IL 37; Interleukin 1 family member 7; Interleukin 1 homolog 4; Interleukin 1 related protein; Interleukin 1 zeta