Human IL-28A ELISA Kit PicoKine®

SKU: EK0969

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IFNL2

Specificity: Natural and recombinant human IL-28A

Background: Interferon lambda-2, also called IFNL2 or IL28A is a class II cytokine receptor ligand related to type I interferons. This gene is mapped to 19q13.2. This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster. It up-regulates MHC class I antigen expression. It also displays antitumor activity. The ligand/receptor complex seems to signal through the Jak-STAT pathway. This gene seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. It seems play a significant role in the antiviral immune defense in the intestinal epithelium.

Immunogen: Expression system for standard: NS0; Immunogen sequence: V26-V200

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Reference:

Uniprot ID: Q8IZJ0

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 282616

Protein Name: Interferon lambda-2

Gene Full Name: interferon lambda 2

Synonyms: Cytokine Zcyto20; IFN lambda 2; IFNL2; IL 28A; IL28A; IL-28A; Interferon lambda 2; Interleukin 28A; ZCYTO20