Human IGFBP2 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

SKU: EZ0384

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IGFBP2

Specificity: Natural and recombinant human IGFBP2

Background: Insulin-like growth factor-binding protein 2 (IGFBP2), also called IBP2, is a protein that in humans is encoded by the IGFBP2 gene. It is mapped to 2q35. By structural analysis, it showed that the IGFBP2 gene consists of 4 exons with 3 introns of lengths 27.0, 1.0, and 1.9 kb. IGFBP2 secreted by metastatic cells recruits endothelia by modulating IGF1 mediated activation of the IGF type-I receptor on endothelial cells. The IGFBP2/IGF1/IGF1R and GAS6/MERTK signaling pathways are regulators of cancer-mediated endothelial recruitment.

Immunogen: Expression system for standard: NS0; Immunogen sequence: E40-Q328

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Reference:

Uniprot ID: P18065

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3485

Protein Name: Insulin-like growth factor-binding protein 2

Gene Full Name: insulin like growth factor binding protein 2

Synonyms: BP2; IBP 2; IBP2; IGF binding protein 2; IGF BP53; IGFBP 2; IGFBP2