Human IFNA2 ELISA Kit PicoKine®

SKU: EK2127

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: IFNA2

Specificity: Natural and recombinant human IFNA2

Background: Interferon alpha-2 is a protein that in humans is encoded by the IFNA2 gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. The encoded protein is effective in reducing the symptoms and duration of the common cold and in treating many types of cancer, including some hematological malignancies and solid tumors. A deficiency of type I interferon in the blood is thought to be a hallmark of severe COVID-19 and may provide a rationale for a combined therapeutic approach.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: C24-E189

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Reference:

Uniprot ID: P01563

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3440

Protein Name: Interferon alpha-2

Gene Full Name: interferon alpha 2

Synonyms: IFNA2; IFNA2A; IFNA2B; IFNA2C; Interferon alpha-2; IFN-alpha-2; Interferon alpha-A; LeIF A