Human ICAM-3 / CD50 ELISA Kit PicoKine®

SKU: EK0940

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: ICAM3

Specificity: Natural and recombinant human ICAM-3

Background: Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a human gene. The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. ICAM3 is closely related to ICAM1, consists of 5 immunoglobulin domains, and binds LFA1 through its 2 N-terminal domains. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM3 has been shown to interact with EZR and Moesin.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q30-H485; homodimer

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Reference:

Uniprot ID: P32942

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3385

Protein Name: Intercellular adhesion molecule 3

Gene Full Name: intercellular adhesion molecule 3

Synonyms: CD50; CDW50; ICAM 3; ICAM R; ICAM3