Human HNMT ELISA Kit PicoKine®

SKU: EK2216

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: HNMT

Specificity: Natural and recombinant human HNMT

Background: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: A2-A292

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Reference:

Uniprot ID: P50135

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 3176

Protein Name: Histamine N-methyltransferase

Gene Full Name: histamine N-methyltransferase

Synonyms: histamine N methyltransferase; HMT; HNMT; HNMT S1; HNMT S2