Human Heterogeneous Nuclear Ribonucleoprotein A1, HNRNP A1 ELISA Kit

SKU: E5396Hu

Size:96 Tests-1 Kit

Background:Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection (PubMed: 17371836). May bind to specific miRNA hairpins (PubMed: 28431233). Binds to the IRES and thereby inhibits the translation of the apoptosis protease activating factor APAF1 (PubMed: 31$498.00|$360.00791). (Microbial infection) May play a role in HCV RNA replication. (Microbial infection) Cleavage by Enterovirus 71 protease 3C results in increased translation of apoptosis protease activating factor APAF1, leading to apoptosis.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:HNRNPA1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.14ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Heterogeneous Nuclear Ribonucleoprotein A1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P09651

MASS(Da):38,747

GeneID:3178

Synonyms:Helix-destabilizing protein;Heterogeneous nuclear ribonucleoprotein A1;Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;hnRNP A1;hnRNP core protein A1;HNRNPA 1;HNRNPA1;Single-strand RNA-binding protein

Gene names:HNRNPA1

Standard solution:96ng/mL