Human Growth Arrest-specific Protein 6, GAS6 ELISA Kit

SKU: E3257Hu

Size:96 Tests-1 Kit

Background:Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. (Microbial infection) Can bridge virus envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry by apoptotic mimicry (PubMed: 21501828). Plays a role in Dengue cell entry by apoptotic mimicry (PubMed: 23084921). Plays a role in Vaccinia virus cell entry by apoptotic mimicry (PubMed: 21501828). Plays a role in ebolavirus and marburgvirus cell entry by apoptotic mimicry (PubMed: 17005688).

Research_area:Cardiovascular

Applications:ELISA

Target_protein:GAS6

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.13ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Growth Arrest-Specific Protein 6

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q14393

MASS(Da):74,925

GeneID:2621

Synonyms:AXL receptor tyrosine kinase ligand;GAS 6;GAS6;GAS-6;Growth arrest-specific protein 6

Gene names:GAS6

Standard solution:96ng/mL