Human Glutathione Synthetase, GSS ELISA Kit

SKU: E5347Hu

Size:96 Tests-1 Kit

Background:Glutathione synthetase (GSS) (EC 6.3.2.3) is the second enzyme in the glutathione (GSH) biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine, to form glutathione. Glutathione synthetase is also a potent antioxidant. It is found in many species including bacteria, yeast, mammals, and plants. In humans, defects in GSS are inherited in an autosomal recessive way and are the cause of severe metabolic acidosis, 5-oxoprolinuria, increased rate of haemolysis, and defective function of the central nervous system. Deficiencies in GSS can cause a spectrum of deleterious symptoms in plants and human beings alike.

Research_area:Signal Transduction; Neuroscience; Cell Biology; Metabolism

Applications:ELISA

Target_protein:GSS

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.028U/mL

Detection range:0.05-20U/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Glutathione synthetase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P48637

MASS(Da):52,385

GeneID:2937

Synonyms:Glutathione Synthase;Glutathione synthetase;GSH synthetase;GSHS;GSH-S;GSS;HEL-S-64p;HEL-S-88n

Gene names:GSS

Standard solution:25.6U/mL