Human Glutamate receptor ionotropic, NMDA 2D,GRIN2D ELISA KIT

SKU: E7210Hu

Size:96 Tests-1 Kit

Background:Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:9489750, PubMed:27616483, PubMed:26875626, PubMed:28126851). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:9489750). {ECO:0000269|PubMed:26875626, ECO:0000269|PubMed:27616483, ECO:0000269|PubMed:28095420, ECO:0000269|PubMed:28126851, ECO:0000269|PubMed:9489750}.

Research_area:

Applications:ELISA

Target_protein:GRIN2D

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.24ng/ml

Detection range:0.5-32ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O15399

MASS(Da):143752

GeneID:2906

Synonyms:GRIN2D GluN2D NMDAR2D

Gene names:GRIN2D

Standard solution:64ng/ml