Human GDF-15 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

SKU: EZ0767

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: GDF15

Specificity: Natural and recombinant human GDF-15

Background: GDF-15 (Growth differentiation factor 15),also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB, is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. Using FISH, the MIC1 gene is mapped to 19p13.2-p13.1. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF15 showed increased expression and secretion during erythroblast maturation. GDF15 functions as an antiinflammatory cytokine by ly interfering with chemokine signaling and integrin activation.

Immunogen: Expression system for standard: CHO; Immunogen sequence: A197-I308

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Uniprot ID: Q99988

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 9518

Protein Name: Growth/differentiation factor 15

Gene Full Name: growth differentiation factor 15

Synonyms: GDF-15; GDF 15; GDF15; MIC 1; MIC1; NAG 1; NRG 1; NSAID activated gene 1 protein; NSAID regulated gene 1 protein; PDF; PLAB; Placental TGF beta; PTGFB