Human G Protein-activated Inward Rectifier Potassium Channel 2, GIRK2 ELISA Kit

SKU: E1100Hu

Size:96 Tests-1 Kit

Background:This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Research_area:Neuroscience

Applications:ELISA

Target_protein:KCNJ6

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.149ng/ml

Detection range:0.3-90ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:G protein-activated inward rectifier potassium Channel 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P48051

MASS(Da):48,451

GeneID:3763

Synonyms:BIR1;G protein-activated inward rectifier potassium Channel 2;GIRK2;GIRK-2;hiGIRK2;Inward rectifier K(+ Channel Kir3.2;KATP2;KATP-2;KCNJ6;KCNJ7;KIR3.2;KPLBS;Potassium Channel, inwardly rectifying subfamily J member 6;

Gene names:KCNJ6

Standard solution:96ng/ml