Human Folypolyglutamate Synthase,FPGS ELISA KIT

SKU: E7155Hu

Size:96 Tests-1 Kit

Background:Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Unsubstituted reduced folates are the preferred substrates. Metabolizes methotrexate (MTX) to polyglutamates. {ECO:0000269|PubMed:8408018, ECO:0000269|PubMed:8408019, ECO:0000269|PubMed:8408021, ECO:0000269|PubMed:8662720}.

Research_area:

Applications:ELISA

Target_protein:FPGS

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.1ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Folypolyglutamate Synthase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q05932

MASS(Da):64609

GeneID:2356

Synonyms:FPGS

Gene names:FPGS

Standard solution:24ng/ml