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GeneBio Systems

Human FGFRL1 ELISA Kit PicoKine®

Human FGFRL1 ELISA Kit PicoKine®

SKU:EK2079

Regular price ¥190,800 JPY
Regular price Sale price ¥190,800 JPY
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Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: FGFRL1

Specificity: Natural and recombinant human FGFRL1

Background: Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene. It is mapped to 4p16.3. The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Immunogen: Expression system for standard: NS0; Immunogen sequence: A25-P378

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Reference:

Uniprot ID: Q8N441

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 53834

Protein Name: Fibroblast growth factor receptor-like 1

Gene Full Name: fibroblast growth factor receptor like 1

Synonyms: fibroblast growth factor receptor like 1; FGFR-5; FGFR5; FHFR; FGFRL1

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